CARBOXAMIDE COMPOUNDS AND USING THEM AS CALPAIN INHIBITORS Russian patent published in 2015 - IPC C07D207/26 C07D211/76 C07D233/34 C07D239/10 A61K31/4015 A61K31/4412 

Abstract RU 2540856 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new carboxamide compounds of formula such as below, their tautomers and pharmaceutically acceptable salts, wherein the values R1, R2, R3a, R3b, R4, Q, Y, A and X are presented in clause 1 of formula .

EFFECT: compounds are cell calpain (calcium-dependent cysteine protease) inhibitors that makes them applicable for treating some diseases related to high activity of calpain.

33 cl, 2 tbl, 75 ex, 7 dwg

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RU 2 540 856 C2

Authors

Mak Khel'Mut

Kling Andreas

Jantos Katja

Meller Akhim

Khornberger Vil'Frid

Khatchins Charl'Z V.

Dates

2015-02-10Published

2010-05-06Filed