FIELD: chemistry.
SUBSTANCE: invention relates to a compound of formula (I-1) 
or a pharmaceutically acceptable salt thereof, where Cy1A is substituted phenyl or unsubstituted or substituted 5–10 membered heteroaryl; wherein the ring atoms of 5–10-membered heteroaryl forming Cy1A consist of carbon atoms and 1, 2 or 3 heteroatoms selected from O, N and S, n1 is equal to 1 or 2 and n2 is equal to 1, which has MASP-2 inhibitory activity, a pharmaceutical composition based thereon and use for preparing a drug for inhibiting MASP-2.
EFFECT: novel compounds which can be used to produce a drug for treating MASP-2-related diseases or disorders are obtained.
21 cl, 38 tbl, 315 ex, 76 dwg
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