LACTOBIFADOL ENCAPSULATION METHOD Russian patent published in 2015 - IPC A61K35/74 A61K9/50 A61K47/38 A61J3/07 B01J13/02 

FIELD: chemistry.

SUBSTANCE: invention relates to microencapsulation of lactobifadol. The method of encapsulating lactobifadol in a shell made of sodium carboxymethyl cellulose is carried out as follows. Lactobifadol is dissolved in dioxane or dimethyl sulphoxide or dimethyl formamide, followed by addition of the obtained lactobifadol solution to a solution of sodium carboxymethyl cellulose in sulphuric ether in the presence of an E472c preparation while stirring at 1000 rps. The lactobifadol and sodium carboxymethyl cellulose are taken in weight ratio of 1:3. Distilled water is then added in amount of 1 ml and the obtained suspension is filtered and dried. The process of producing lactobifadol microcapsules is carried out at 25°C for 20 min.

EFFECT: method speeds up the microencapsulation process and reduces losses (high mass output).

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