PHARMACEUTICAL COMPOSITION IN FORM OF LYOPHILISATE FOR PREPARATION OF SOLUTION FOR PARENTERAL APPLICATION AND METHOD OF OBTAINING THEREOF Russian patent published in 2015 - IPC A61K9/19 A61K31/44 

FIELD: medicine.

SUBSTANCE: pharmaceutical composition in form of lyophilisate for preparation of solution for parenteral application for tuberculosis treatment represents lyophilisate of prothionamide salt, which includes in composition additional substances, and in case of addition of pharmaceutically acceptable diluents is applicable for intravenous introduction. Pharmaceutical composition is obtained by dissolution of prothionamide substance in pharmaceutically acceptable acid, taken in equimolar ratio or with up to 20% excess, sterile filtering of solution, pouring in reservoirs and lyophilic drying. Finished medication is provided with pH corrector (sodium hydrocarbonate solution).

EFFECT: medication is stable in storage and is applied for preparation of solution for intravenous drip-feed.

9 cl, 2 ex