FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the field of medicine, namely to immunology and allergology, and can be used for the treatment of allergy to house dust mites. For this purpose an allergotropine is obtained by a method of chemical conjugation of an allergoid and synthetic highly molecular immunomodulator Polyoxidonium. The allergotropine contains 1000±200 PNU of the allergoid of house dust mites Dermatophagoides pteronyssinus or Dermatophagoides farinae and 6.25±1.25 mg of Polyoxidonium.
EFFECT: obtaining the allergotropines, based on the allergoid forms of allergens of house dust mites Dermatophagoides pteronyssinus or Dermatophagoides farinae, possessing more expressed immunogenic and hyposensitising properties in comparison with the native allergen, makes it possible to carry out the effective treatment of allergy by ASIT method.
2 ex, 2 tbl, 2 dwg
Title | Year | Author | Number |
---|---|---|---|
ALLERGOTROPIN FOR TREATING POLLINOSIS AND METHOD FOR TREATING POLLINOSIS | 2001 |
|
RU2205661C2 |
COMPLEX PREPARATION BASED ON ALLERGENS OF BIRCH POLLEN AND MURAMYLPEPTIDES | 2012 |
|
RU2537225C2 |
RECOMBINANT PLASMID DNA pQE30/derf2L CODING PROTEIN der f 2L OF MITE Dermatophagoides farinae, AND BACTERIAL STRAIN Escherichia coli M15/pQE30/derf2L - PRODUCER OF SUCH PROTEIN | 2012 |
|
RU2522817C9 |
METHOD OF SUBLINGUAL ALLERGEN-SPECIFIC IMMUNOTHERAPY (SASI) OF POLLINOSIS WITH HYPOSENSITIZATION AGENT | 2019 |
|
RU2725633C1 |
METHOD TO ASSESS HYPERSENSITIVITY TO HISTAMINE RELEASE FROM WHOLE BLOOD LEUKOCYTES | 2016 |
|
RU2622003C1 |
METHOD OF TREATING PATIENTS WITH ALLERGIC RHINITIS WITH DISTURBED MICROBE LANDSCAPE OF NASAL MUCOSA | 2019 |
|
RU2711525C1 |
METHOD OF TREATING CHRONIC RECURRENT ALLERGIC DISEASES OF NASAL MUCOSA AND PARANASAL SINUSES BY ENDONASAL AUTOLYMPHOCYTE THERAPY | 2009 |
|
RU2411048C1 |
ANTI-ALLERGIC AGENTS | 2017 |
|
RU2690430C2 |
METHOD OF PRODUCING ALLERGEN EXTRACT | 2011 |
|
RU2706685C2 |
METHOD OF OBTAINING ALLERGEN EXTRACT | 2011 |
|
RU2572230C2 |
Authors
Dates
2015-04-20—Published
2013-08-15—Filed