FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a compound (I) 
or its pharmaceutically acceptable salt, which possess properties of selective phosphodiesterase inhibitors, and can be used for treating male erectile dysfunction. In compound (I) R1 represents C1-C6alkyl; R2 represents C1-6alkyl; R3 represents C1-C6alkyl; R4 represents C1-C6 alkyl; R5 means H. The above salt is formed by the compound of formula (I) and an acid specified in citric acid, oxalic acid, hydrochloric acid, sulphuric acid, phosphoric acid, maleic acid, fumaric acid, tartaric acid, hydroxysuccinic acid, succinic acid, methane sulphonic acid or n-toluene sulphonic acid. A preferential compound is 5-[2-ethoxy-5-(4-methyl-1-homopiperazinylsulphonyl)]phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one.
EFFECT: preparing the pharmaceutically acceptable salt that possesses the properties of selective phosphodiesterase inhibitors.
7 cl, 1 tbl, 5 ex
| Title |
Year |
Author |
Number |
| PYRAZOLEPYRIMIDINONES FOR TREATMENT OF IMPOTENTS |
1994 |
- Piter Ehllis
- Nikolas Kennet Terrett
|
RU2130776C1 |
| METHOD FOR PREPARING DERIVATIVES OF PYRAZOLOPYRIMIDINONE FOR TREATMENT OF IMPOTENCY |
2001 |
- Joo Moo-Khi
- Kim Von-Bae
- Chang Min-Sun
- Kim Soon-Khoe
- Kim Dong-Sung
- Bae Chul-Dzun
- Kim Jong-Duk
- Kim Eun-Kha
|
RU2236410C2 |
| PIRAZILE PYRIMIDINONES FOR IMPOTENCY TREATMENT |
1994 |
- Ehllis Piter
- Terrett Nikolas Kennet
|
RU2373938C9 |
| NEW COMPOUND FOR IMPOTENCE TREATMENT |
2002 |
|
RU2279433C2 |
| METHOD FOR TREATING MALE PATIENTS FOR ERECTILE DYSFUNCTION AND HIGH LIBIDO |
2001 |
|
RU2303981C2 |
| DERIVATIVES OF 2-SUBSTITUTED PHENYL-5,7-DIHYDROCARBYL-3,7-DIHYDROPYRROLO[2,3-d]PYRIMIDIN-4-ONES, THEIR PREPARING AND PHARMACEUTICAL USING |
2004 |
- Van Junfehn
- Chzhao Kehtszjun'
|
RU2323220C2 |
| COMPOUND POSSESSING INHIBITORY ACTION ON PHOSPHODIESTERASE TYPE 5, AND METHOD FOR PREPARING IT |
2010 |
|
RU2547465C2 |
| PHARMACEUTICAL COMPOSITION, CONTAINING SILDENAFIL OR ALPROSTADIL, MINOXIDIL OR EUPHYLLIN, TESTOSTERON OR YOHIMBINE AND LIPOSOMES FOR LOCAL APPLICATION |
2010 |
- Klopotenko Leonid Leonidovich
|
RU2482847C2 |
| DERIVATIVES OF 6,7-DIHYDRO-3H-OXAZOLO[3,4-α]PYRAZINE-5,8-DIONE |
2011 |
- Sacurai Sergio Luiz
- Zaim Marcio Henrique
- Touzarim Carlos Eduardo Da Costa
- Keppler Artur Franz
- De Nucci Gilberto
|
RU2581831C2 |
| PYRAZOLOPYRIMIDINONES, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITION OF CYCLIC GUANOSINE-3',5'-MONOPHOSPHATE PHOSPHODIESTERASE |
1992 |
- Ehndrju Simon Bell
- Nikolas Kennet Terrett
|
RU2114113C1 |
