TREATMENT OF VAGINAL ATROPHY IN WOMEN WITH RISK OF CARDIOVASCULAR PATHOLOGY Russian patent published in 2015 - IPC A61K31/566 A61P15/00 A61P15/02 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to gynaecology, and can be used for a method of prevention and/or treatment of urogenital atrophy in women, including the vaginal introduction of pharmaceutical compositions with estriol, as well as for the application of estriol in the production of a pharmaceutical composition with a possibility of self-restriction of estriol absorption. The said women have the high possibility of development of a cardiovascular pathology, or suffer or suffered from the cardiovascular pathology. Estriol is introduced in a dose, smaller or equal to 0.1 mg/day. An area under the estriol concentration curve depending on the time constitutes less than 500 pg/ml·h after the introduction of repeated doses one time per day for the time period from 1 to 4 weeks.

EFFECT: group of inventions provides efficient and safe treatment.

24 cl, 7 tbl, 1 dwg