FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new (R)-stereoisomers of substituted 2-thioxo-imidazolidin-4-ones of formula 1 or to spiroanalogues thereof, which possess the properties of an androgen receptor agonist, to versions of a method for producing them, and to intermediate compounds 2.1-2.4 for producing compounds of formula 1. The invention also refers to a pharmaceutical composition presented in the form of tablets, capsules, injections. In formula 1 
R1 represents OH, NH2, or OR4 group; R2 and R3 represent methyl, or R2 and R3 represent CH2-CH2 group; R4 represent C1-C4alkyl or cyclopropyl. The compounds 2.1-2.4 are described by structural formulas: 
EFFECT: compounds of formula 1 can be used for producing the medicinal product applicable for treating a cancer disease, such as prostate cancer, breast cancer.
17 cl, 1 tbl, 10 ex
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