FIELD: chemistry.
SUBSTANCE: invention relates to encapsulation, particularly to a method of producing albendazole nanocapsules in a sodium alginate envelope. The disclosed method includes adding albendazole to a sodium alginate suspension in hexane in the presence of an E472c preparation while mixing at 1000 rps. The weight ratio of albendazole and sodium alginate is 1:3 or 3:1. Further, 1,2-dichloroethane is added. The obtained suspension of nanocapsules is filtered, washed and dried. The process of producing the nanocapsules is carried out at 25°C for 20 minutes.
EFFECT: invention provides a simpler and faster process of producing nanocapsules, reduces losses during production thereof (high mass output).
3 ex, 1 dwg
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Authors
Dates
2015-07-27—Published
2014-04-07—Filed