METHOD OF PRODUCING ALBENDAZOLE NANOCAPSULES Russian patent published in 2015 - IPC A61K31/4184 A61K9/51 A61K47/36 A61J3/07 B01J13/02 B82B3/00 

Abstract RU 2558082 C1

FIELD: chemistry.

SUBSTANCE: invention relates to encapsulation, particularly to a method of producing albendazole nanocapsules in a sodium alginate envelope. The disclosed method includes adding albendazole to a sodium alginate suspension in hexane in the presence of an E472c preparation while mixing at 1000 rps. The weight ratio of albendazole and sodium alginate is 1:3 or 3:1. Further, 1,2-dichloroethane is added. The obtained suspension of nanocapsules is filtered, washed and dried. The process of producing the nanocapsules is carried out at 25°C for 20 minutes.

EFFECT: invention provides a simpler and faster process of producing nanocapsules, reduces losses during production thereof (high mass output).

3 ex, 1 dwg

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RU 2 558 082 C1

Authors

Krolevets Aleksandr Aleksandrovich

Bogachev Il'Ja Aleksandrovich

Dates

2015-07-27Published

2014-04-07Filed