DRUG FORM FOR hGH AND rhIGF-1 COMBINATION+ Russian patent published in 2015 - IPC A61K38/27 A61K38/30 A61K47/18 A61K47/00 A61K9/08 A61J3/00 

Abstract RU 2558821 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmaceutics. Described is drug form of combined compositions of growth hormone (GH) and insulin-like growth factor (IGF-1). Composition includes aggregation-preventing substance, histidine or citrate buffer, non-ionic surface-active substance, and optionally contains preservative, tonicity modifier or filler. As aggregation-preventing substance arginine is used, with sodium chloride being used as tonicity modifier. Method of composition obtaining is also disclosed.

EFFECT: invention provides stable transparent pharmaceutical compositions without formation of aggregates.

18 cl, 2 dwg, 14 tbl, 10 ex

Similar patents RU2558821C2

Title Year Author Number
PHARMACEUTICAL COMPOSITION COMPRISING GROWTH HORMONE, AMINO ACID AND NON-IONIC DETERGENT 1997
  • B'Ern Seren
  • Serensen Khans Khol'Megor
  • Langballe Peter
  • Larsen Sil'Ke Meller
  • Ehbbekhej Kirsten
  • Khansen Birte Ljukkegor
RU2236250C2
AQUEOUS PHARMACEUTICAL COMPOSITION OF A RECOMBINANT MONOCLONAL ANTIBODY TO TNF-α 2017
  • Lomkova Ekaterina Aleksandrovna
  • Yakovlev Aleksandr Olegovich
  • Shitikova Viktoriya Olegovna
  • Ryakhovskaya Anastasiya Mikhajlovna
  • Morozov Dmitrij Valentinovich
RU2764521C2
RECOMBINANT MONOCLONAL ANTIBODY TO TNF-ALPHA AQUEOUS PHARMACEUTICAL COMPOSITION 2016
  • Morozov Dmitrij Valentinovich
  • Lomkova Ekaterina Aleksandrovna
  • Yakovlev Aleksandr Olegovich
  • Shitikova Viktoriya Olegovna
  • Ryakhovskaya Anastasiya Mikhajlovna
  • Ivanov Roman Alekseevich
RU2665966C2
STABLE LIQUID PHARMACEUTICAL COMPOSITION 2018
  • Jayaraman, Murali
  • Nair, Pravin
  • Kaur, Navneet
  • T, Deepak
RU2773747C2
STABLE PHARMACEUTICAL COMPOSITION 2017
  • Dzhajaraman Murali
  • Nair Pravin
  • Kanakadurga Lakshmi
  • Kaur Navnit
  • T Dipak
RU2736830C2
ANTIBODY CONTAINING PREPARATION 2017
  • Saeki Atsusi
  • Nisidzava Se
  • Sasaki Khitosi
  • Imaj Tifumi
  • Igava Tomoyuki
RU2748046C2
FORMULATIONS OF SINGLE DOMAIN ANTIGEN BINDING MOLECULES 2013
  • Fernandes Dzhejson E.
  • Dikson Deniel A.
  • Paulson Andrea
RU2683861C2
PHARMACEUTICAL FORMULA CONTAINING HUMAN ANTI-TSLP ANTIBODY 2016
  • Ikeda Megumi
  • Tikusi Akinori
RU2794148C2
STABLE PHARMACEUTICAL PREPARATION BASED ON THE PD-1 ANTIBODY AND ITS USE IN MEDICINE 2016
  • Li Tsze
  • Yan Chzhen
  • Van Pinpin
  • Fan Yan
  • Tao Vejkan
  • Chzhan Lyanshan
  • Sun Pyaoyan
RU2731418C2
LIQUID COMPOSITION OF HUMAN GROWTH HORMONE WITH PROLONGED ACTION 2011
  • Khong Sung Khi
  • Li Biung Sun
  • Im Dae Seong
  • Li Dzae Min
  • Bae Sung Min
  • Kvon Se Chang
RU2623026C2

RU 2 558 821 C2

Authors

Gopinat Ehnona

Park S'Juzan

Arakava Tsutomu

Rishar Zhoehl'

Feh Fabio

Dates

2015-08-10Published

2010-11-17Filed