NOVEL TUMOUR BIOMARKER Russian patent published in 2015 - IPC C07K14/47 C07K16/18 G01N33/53 A61K39/395 A61K35/00 

Abstract RU 2567005 C2

FIELD: medicine.

SUBSTANCE: invention relates to biochemistry. Method includes determination of level of polypeptide with said sequence in plasma by means of antigen, where Thr90 of polypeptide is phosphorylated. Also diagnostic sets for detection of presence of tumour metastases are described, for screening for presence of tumour among high risk population, for determination of prognosis for patient, for determination of efficiency of surgery, radiotherapy or chemical therapy with respect to patient with tumour, and/or determination of the time when treatment must be stopped. Diagnostic sets include polypeptide with sequence, given in materials, where Thr90 of polypeptide is phosphorylated.

EFFECT: described are methods for detection of presence or metastases of tumour, screening for presence of tumour among high risk population, prognosis for patient with tumour, determination of efficiency of surgery, radiotherapy or chemical therapy.

27 cl, 20 dwg, 18 ex

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RU 2 567 005 C2

Authors

Lo Junchzhan

Sun Sjaomin'

Van Sjaofyn

Chzho Vehj

Chan Godun

Fu Jan'

Dates

2015-10-27Published

2010-08-11Filed