PHARMACEUTICAL DOSED FORM FOR PERORAL INTRODUCTION OF BCL-2 FAMILY INHIBITOR Russian patent published in 2015 - IPC A61K9/00 A61K9/14 A61K31/5377 

Abstract RU 2568599 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to a pharmaceutical dosed form, which includes the product in the form of a solid dispersion, including N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulphanyl)methyl)propyl)amino)-3-((trifluoromethyl)-sulphonyl)benzosulphonamide or its salt, hydrate or solvate, at least, one pharmaceutically acceptable polymer and, at least, one pharmaceutically acceptable solubiliser.

EFFECT: invention is aimed at the method of manufacturing the pharmaceutical dosed form and application of the dosed form in the treatment of proliferative disorders.

19 cl, 8 dwg, 6 tbl, 7 ex

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Authors

Pakkhojzer Klaudia

Shtajger Norbert

Lipol'D Bernd

Kostelak Dratsen

Knoblokh Martin

Dates

2015-11-20Published

2010-06-08Filed