METHOD OF INCREASING LEVOMYCETINUM (CHLORAMPHENICOL) EFFICIENCY Russian patent published in 2015 - IPC A61K31/165 C07C7/148 C07C7/20 

FIELD: chemistry.

SUBSTANCE: 5 g of levomycetinum are dissolved in 100 ml of distilled water, activated with silver ions in concentration 1.0 mg in 100 ml, first polymerisation of levomycetin solution with glutaraldehyde is carried out at 40°C for 2-3 days, after which second polymerisation of levomycetin solution is carried out with 0.2-0.3% of etonium at 40°C for 2-3 days, with content of glutaraldehyde and etonium in 100 ml of solution constituting 0.1% and 0.2-0.3% respectively.

EFFECT: reduction of preparation concentration with increase of biocidal activity with respect to association of pathogenic microorganisms.

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