METHOD FOR ENHANCEMENT OF EFFICACY OF E.coli RESISTANT ANTIBIOTICS Russian patent published in 2013 - IPC A61K31/00 C12Q1/04 A61K31/04 

Abstract RU 2476210 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: method under the invention involves detoxification and polymerisation of the tested antibiotics 150-200 mg/ml at first in 0.15±0.05% glutaric aldehyde at 38-40°C for 2-3 days, then in 0.1% aethonium or 0.1% alkyl dimethyl benzyl ammonium or 0.1% Biopague D at 38-40°C for 2-3 days.

EFFECT: use of the method provides 1,5-2,0 times higher activity of the antibiotic as compared to commercial preparations and ensures the bactericidal efficacy to antibiotic-resistant Ecoli.

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RU 2 476 210 C1

Authors

Evglevskij Anatolij Alekseevich

Evglevskij Dmitrij Anatol'Evich

Khudjakov Sergej Ivanovich

Timkova Elena Anatol'Evna

Tatarnikov Kirill Viktorovich

Dates

2013-02-27Published

2011-10-13Filed