FIELD: medicine, pharmaceutics.
SUBSTANCE: method under the invention involves detoxification and polymerisation of the tested antibiotics 150-200 mg/ml at first in 0.15±0.05% glutaric aldehyde at 38-40°C for 2-3 days, then in 0.1% aethonium or 0.1% alkyl dimethyl benzyl ammonium or 0.1% Biopague D at 38-40°C for 2-3 days.
EFFECT: use of the method provides 1,5-2,0 times higher activity of the antibiotic as compared to commercial preparations and ensures the bactericidal efficacy to antibiotic-resistant Ecoli.
2 ex
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Authors
Dates
2013-02-27—Published
2011-10-13—Filed