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(19)

(11)

2 572 621

(13)

(51)

IPC

C07D405/14(2006-01-01)

C07D413/14(2006-01-01)

C12N1/00(2006-01-01)

A61K31/5355(2006-01-01)

A61K31/4025(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2012131247/04, 2010-12-17

(24)

Start date

2010-12-17

(22)

Actual filing date

2010-12-17

(45)

Published

2016-01-20

(72)

Inventor

Singkh SheoPolishuk Dzhon D.Zink Debora L.Khenil'Jud Ol'GaGetts MajklVisente FransiskaOlsen Dehvid BrajanSmit Skott Nobl

(73)

Holder

Merk Sharp I Doum Korp.Merk Sharp Ehnd Domeh De Ehspan'Ja

KIBDELOS PORANGIUM EXTRACTS AS ANTIBACTERIAL AGENTS Russian patent published in 2016 - IPC C07D405/14 C07D413/14 C12N1/00 A61K31/5355 A61K31/4025 A61P31/00

Abstract RU 2572621 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to an antibacterial composition containing one or more refined compounds specified in compounds of formula:

wherein R¹ and R² are independently specified in a group consisting of hydrogen and halogen; and R³ are specified in a group consisting of hydrogen and C₁-C₆alkyl; and formula

wherein: R¹ and R² are independently specified in a group consisting of hydrogen and halogen; and R³ represents hydrogen, and pharmaceutically acceptable salts. These compositions are acceptable in treating and/or preventing bacterial infections and associated diseases and conditions in humans and animals. The invention also refers to a method for producing these compositions by fermentation and precipitation, partial synthesis and complete synthesis; to methods for bacterial growth inhibition, as well as to biologically pure cultures of bacterial strains, which are used to produce these compounds.

EFFECT: producing the compositions, which are acceptable in treating and/or preventing bacterial infections and associated diseases and conditions in humans and animals.

20 cl, 3 dwg, 3 tbl, 3 ex

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RU 2 572 621 C2

Authors

Singkh Sheo

Polishuk Dzhon D.

Zink Debora L.

Khenil'Jud Ol'Ga

Getts Majkl

Visente Fransiska

Olsen Dehvid Brajan

Smit Skott Nobl

Dates

2016-01-20—Published

2010-12-17—Filed