HYDROXYALKYLTHIADIAZOLE DERIVATIVES Russian patent published in 2020 - IPC C07D417/14 A61K31/433 A61P31/00 

Abstract RU 2737892 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of general formula (I) or a hydrate thereof, where R is (C1-C3) alkyl, and A is the following formula:

or ,

provided that the general formula (I) includes tautomers with hydrogen in different positions of the imidazole ring. Invention also relates to a pharmaceutical composition for treating a bacterial infectious disease, where the bacterial infectious disease is caused by gram-positive bacteria, selected from species of genus Staphylococcus, Streptococcus, Enterococcus and Clostridium, or gram-negative bacteria Neisseria gonorrhoeae, based on said compound.

EFFECT: technical result is obtaining a novel compound which can be used in medicine for treating bacterial infectious diseases.

15 cl, 9 dwg, 5 tbl, 15 ex

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RU 2 737 892 C1

Authors

Khera, Manoj Kumar

Mathur, Tarun

Sattigeri, Jitendra A.

Masuda, Nobuhisa

Soneda, Tsuyoshi

Kagoshima, Yoshiko

Konosu, Toshiyuki

Suzuki, Tetsuya

Yamaoka, Makoto

Itooka, Ryo

Dates

2020-12-04Published

2016-09-28Filed