FIELD: medicine.
SUBSTANCE: as medications administered are: methotrexate 15 mg per week intake, folic acid 5 mg per week intake, movalis 15 mg per day intake. Laser therapy is administered in differential way depending on degree of disease activity and leptin level. In case of second stage of rheumatoid arthritis - index DAS28 3.2-5.1, leptin level, equal or lower than 6.4±0.42 pg/ml, 7 daily procedures of intravenous laser irradiation are carried out. Radiating head KL-VLOK with wavelength 635 nm, power at the end of disposable light guide 1.5 mW, exposure time 15 minutes and laser head KL-VLOK-365 with wavelength 365 nm, power at the end of light guide 1.0 mW, exposure time 5 minutes, are alternated. In case of third degree of activity index DAS28 is higher than 5.1, leptin level is equal or is higher than 8.8±0.72 pg/ml, 10 procedures are carried out. Radiating head KL-VLOK with wavelength 635 nm, power at outlet of disposable light guide 1.5-2.0 mW, exposure time 15 minutes and laser head KL-VLOK-365 with wavelength 365 nm, power at outlet of disposable light guide 1.0 mW, time of exposure 5 minutes.
EFFECT: method makes it possible to reduce frequency of exacerbations, reduce expression of clinical manifestations, reduce drug load on patient, provides earlier arrest of disease symptoms due to differentiated approach in case of administration of intravenous laser irradiation of blood and its normalising action on dynamics of leptin level and reduction of disease activity degree.
2 ex
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Authors
Dates
2016-01-20—Published
2013-12-16—Filed