COMPOSITIONS AND METHODS, INCLUDING ALKYLGLYCOSIDES, FOR STABILISATION OF PROTEIN-CONTAINING COMPOSITIONS Russian patent published in 2016 - IPC A61K39/395 A61K31/7028 A61K9/08 

Abstract RU 2575830 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to field of pharmaceutics and deals with aqueous composition, containing antibody and alkylglycoside, which has CNC value about 1.0 mM or higher in water at 25°C, where alkylglycoside is present in concentration, which is lower than alkylglycoside CMC value in water at 25°C. Also claimed are method of antibody aggregation inhibition and method for prevention of antibody oxidation in aqueous solution with application of aqueous composition.

EFFECT: increased antibody stability in therapeutically suitable compositions.

33 cl, 16 dwg, 2 tbl, 3 ex

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RU 2 575 830 C2

Authors

Esue Osigve

Sharma Vikas K.

Dates

2016-02-20Published

2011-06-23Filed