FIELD: pharmaceutics.
SUBSTANCE: group of inventions relates to pharmaceutics and refers to pharmaceutical composition containing antibody and polyoxyethylene (POE) sorbitan, without polysorbate, and also method of preparing composition and method of stabilising protein-containing finished forms.
EFFECT: group of inventions provides improved stability by preventing proteins aggregation in aqueous solutions.
14 cl, 11 dwg
Title | Year | Author | Number |
---|---|---|---|
COMPOSITIONS AND METHODS, INCLUDING ALKYLGLYCOSIDES, FOR STABILISATION OF PROTEIN-CONTAINING COMPOSITIONS | 2011 |
|
RU2575830C2 |
HIGHLY CONCENTRATED COMPOSITIONS OF ANTIBODIES AND PROTEINS | 2004 |
|
RU2332986C2 |
RECOMBINANT MONOCLONAL ANTIBODY TO TNF-ALPHA AQUEOUS PHARMACEUTICAL COMPOSITION | 2016 |
|
RU2665966C2 |
AQUEOUS PHARMACEUTICAL COMPOSITION OF A RECOMBINANT MONOCLONAL ANTIBODY TO TNF-α | 2017 |
|
RU2764521C2 |
SINGLE-STRANDED CD40 RECEPTOR AGONIST PROTEINS | 2016 |
|
RU2745801C2 |
STABLE PROTEIN PREPARATIONS CONTAINING MOLAR EXCESS OF SORBITOL | 2015 |
|
RU2689145C2 |
METHOD OF PURIFYING APO-2 LIGAND/TRAIL VIA COLD CRYSTALLISATION | 2006 |
|
RU2435781C2 |
COMPOSITIONS OF ANTIBODIES | 2014 |
|
RU2694055C2 |
COMPOSITIONS OF ANTIBODIES | 2005 |
|
RU2426554C2 |
HUMANISED ANTIBODIES WITH INCREASED STABILITY | 2015 |
|
RU2684703C2 |
Authors
Dates
2016-05-20—Published
2011-03-21—Filed