ANTIVIRAL AGENT BASED ON SERRATIA-FAMILY BACTERIA NUCLEASE Russian patent published in 2016 - IPC A61K38/46 C12N9/14 C12N1/20 

Abstract RU 2580242 C2

FIELD: bioengineering.

SUBSTANCE: invention relates to asubstance with antiviral activity with respect to an influenza virus, variolovaccine, mousepox virus and herpes virus of the 2nd type. It discloses the Serratia-family nucleases-based bacteria. As the source of the latter it includes the purified culture fluid of the Serratia plymuthica bacteria strain with the PNA-like activity of 190.0-926 unit/ml and protein content of 3.6-13.5 mg/ml. The said Serratia plymuthica bacteria strain can represent the Serratia plymuthica bacteria strain Dg-91 or Dg-98, or Bp-868 or Az-372 deposited in the collection of bacteria, bacteriophages and fungi of the Federal budget scientific Centre "State R&D centre of virology and biotechnology "Vector" enumerated as B-1288, or B-1297, or B-1296, or B-1285, respectively. The invention may be used in medicine and microbiological industry.

EFFECT: higher efficiency.

6 cl, 4 tbl, 22 ex

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RU 2 580 242 C2

Authors

Puchkova Larisa Ivanovna

Ibragimova Zhanna Borisovna

Mazurkova Natalja Alekseevna

Andreeva Irina Sergeevna

Dates

2016-04-10Published

2014-07-29Filed