FIELD: bioengineering.
SUBSTANCE: invention relates to asubstance with antiviral activity with respect to an influenza virus, variolovaccine, mousepox virus and herpes virus of the 2nd type. It discloses the Serratia-family nucleases-based bacteria. As the source of the latter it includes the purified culture fluid of the Serratia plymuthica bacteria strain with the PNA-like activity of 190.0-926 unit/ml and protein content of 3.6-13.5 mg/ml. The said Serratia plymuthica bacteria strain can represent the Serratia plymuthica bacteria strain Dg-91 or Dg-98, or Bp-868 or Az-372 deposited in the collection of bacteria, bacteriophages and fungi of the Federal budget scientific Centre "State R&D centre of virology and biotechnology "Vector" enumerated as B-1288, or B-1297, or B-1296, or B-1285, respectively. The invention may be used in medicine and microbiological industry.
EFFECT: higher efficiency.
6 cl, 4 tbl, 22 ex
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Authors
Dates
2016-04-10—Published
2014-07-29—Filed