ARTIFICIAL PLASMA EXTENDER Russian patent published in 2016 - IPC A61K31/718 A61K31/194 A61P7/08 

Abstract RU 2582219 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly to plasma substituting solutions, and can be used in transfusion in treatment of hypovolemic states of different aetiology. Disclosed plasma solution contains hydroxyethyl starch and sodium fumerate as an electrolyte in following ratio: hydroxyethyl starch 58-62 g/l, sodium fumerate 15-17 g/l, water for injections up to 1,000 ml and has an osmolarity value of 280-320 mosm/l.

EFFECT: invention provides replacement of volume of circulating fluid and restoration of hemocirculation and blood rheological properties, and also provides a specific cardiotonic effect, that is sharply increases minute volume of blood circulation and stroke output in short period of time after beginning of treatment, which effectively improves cardiac activity and restores parameters of acid-base balance of body.

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RU 2 582 219 C2

Authors

Chechetkin Aleksandr Viktorovich

Svintsova Olga Vladimirovna

Ivanov Andrej Jurevich

Alekseeva Natalija Nikolaevna

Gerasimova Marija Leonidovna

Dates

2016-04-20Published

2014-05-21Filed