METHOD OF TREATING NEUROSIS Russian patent published in 2016 - IPC A61K33/06 A61K31/7004 A61P25/18 

Abstract RU 2582971 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to neurology. What is presented is a method of treating neurosis, which involves using mechanically activated amorphous gluconic acid calcium salt with homogenous diffuse halo in its X-ray powder diffraction pattern characterised by gravity centre line displacement of an absorption band of 3000-3600 cm-1 to a greater wave number range by a value of no more than 200 cm-1, presence of an absorption band at frequencies 3308±20, 2933±10, 1602±10, 1420±10 with an arm of 1260±40, 1085±10, 1044±10, 877±10, 682±10, 577±10 cm-1 and a secondary absorption band at frequencies 947±10 cm-1 in the IR spectrum, a decrease in endothermic peaks in the temperature range of 125-165°C and a peak increase in the temperature range of 30-100°C as shown by differential thermal analysis, presence of an intensive single line with a splitting factor from 2.000 to 2.006 and a width from 8 to 9 E in the electron paramagnetic resonance spectrum, a manifestation of an unresolved fine-structure broad line within the range of 60-90 and 170-190 mln-1 in 13C NMR spectra, resonant line displacement of their aquatic solutions within the range of 62.8-179.2 mln-1 by a value of no more than 0.1 mln-1 in 13C NMR spectra, resonant line displacement of their aquatic solutions within the range of 1.2-4.95 mln-1 by a value of no more than 0.02 mln-1 in 1H NMR spectra, an increase of peak intensities 160 t/g of mass spectra of at least 2.5 times as much and peak intensities 780-1000 t/g of ethanolic extracts of their solutions of at least three times as much in mass spectrometric analysis. The above amorphous gluconic acid calcium salt is administered orally once to four times a day in doses 0.5-2.0 g for 30-40 days every 1-2 weeks in the form of powder, and/or tablets, and/or capsule, and/or solution, until remission is achieved.

EFFECT: recovery of normal functioning of nerve cells and enables avoiding the use of anxiolytics, antidepressants or neuroleptics.

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RU 2 582 971 C2

Authors

Jakimov Anton Vladimirovich

Konygin Grigorij Nikolaevich

Rybin Dmitrij Stanislavovich

Elsukov Evgenij Petrovich

Jakimov Kirill Antonovich

Osetrov Anatolij Sergeevich

Strelkov Nikolaj Sergeevich

Shatsillo Oleg Igorevich

Dates

2016-04-27Published

2013-11-11Filed