SOLID DOSAGE FORM OF PROCARBAZINE OF IMMEDIATE RELEASE AND PREPARATION METHOD THEREOF Russian patent published in 2016 - IPC A61K9/48 A61K33/06 A61K47/10 A61K47/36 A61P35/00 A61K31/166 

Abstract RU 2586290 C1

FIELD: pharmaceutics.

SUBSTANCE: disclosed is a method for preparing solid procarbazine dosage form, in which at temperature of 40-45 °C mannitol, procarbazine hydrochloride and magnesium stearate are mixed, and moistened with starched aqueous solution. Granulates are dried for 10-15 minutes, powdered with mixture of maize starch and talc and encapsulated.

EFFECT: disclosed is method for preparing of procarbazine solid dosage form, having anti-tumour activity.

1 cl, 2 tbl

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Authors

Dates

2016-06-10Published

2014-12-18Filed