SOLID INDIVIDUAL HIGH 2-ETHYL-6-METHYL-3-PYRIDIN-3-OLE HYDROCHLORIDE DOSAGE FORM AND METHOD FOR PREPARING IT Russian patent published in 2012 - IPC A61K9/20 A61K31/44 A61P9/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to chemical-pharmaceutical industry, and concerns a solid individual dosage forms exhibiting antistress, moderate tranquilising, nootropic, antiamnestic and antihypoxic action, containing as an active ingredient, an effective amount of 2-ethyl-6-methyl-3-pyridin-3-ole hydrochloride and pharmaceutically acceptable excipients, which contains 65.0-92.5 wt % of 2-ethyl-6-methyl-pyridin-3-ole hydrochloride, 25.6-2.5 wt % twice-substituted calcium phosphate as an excipient, 0.4-1.9 wt % of oxypropylcellulose as a binding agent and 9.0-0.6 wt % of flowing and anti-adhesion substances. Said dosage form may be presented in the form of a optionally coated marked tablet.

EFFECT: invention provides a method for making said solid individual dosage form, has high bioavailability and shelf life to 5 years.

3 cl, 9 ex, 7 tbl