METHOD OF TREATING PATIENTS WITH DESTRUCTIVE FORMS OF PULMONARY TUBERCULOSIS Russian patent published in 2016 - IPC A61K31/4196 A61K31/424 A61P31/06 

FIELD: medicine.

SUBSTANCE: invention can be used in integrated treatment of patients with destructive forms of pulmonary tuberculosis. For this purpose, on background of course of anti-tuberculosis therapy according to standard conditions from first day in therapeutic course includes Thiotriazoline preparation, and patient is orally administered 200 mg of Tubosan 1 time a day after meals. Thiotriazoline is administered as follows: first 15 days intravenously in dose 4.0 ml diluted in 200.0 ml of 0.9 % sodium chloride, from 16th to 60th day orally in a dose of 100 mg 1 time a day after meals. Tubosan and Thiotriazoline preparations are withdrawn, and course of anti-tuberculosis therapy according to standard conditions is continued.

EFFECT: method enables to reduce time of resorption infiltration, cavity closure and abacillation, improves parameters of immune and cytokine status, free-radical oxidation with reduction of frequency of adverse reactions on antituberculous preparations.

1 cl, 6 tbl, 2 ex