INJECTABLE COMPOSITION BASED ON GROUP B VITAMINS AND LIDOCAINE Russian patent published in 2016 - IPC A61K9/08 A61K31/51 A61K31/4415 A61K31/714 A61K47/48 A61P25/00 

Abstract RU 2589824 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry and medicine and represents a pharmaceutical composition for parenteral administration in diseases and disorders associated with syndromes of nervous system of various origin, including from 4.5 to 6.25 wt% thiamine hydrochloride, from 4.5 to 5.5 wt% pyridoxine hydrochloride, from 0.045-0.055 % cyanocobalamin, from 0.9 to 1.1 wt% lidocaine hydrochloride, 0.105 to 0.095 wt% sodium hexapolyphosphate, from 0.95 to 1.05 wt% linear sodium polyphosphate, from 0.009-0.015 wt% potassium ferricinide (III), sodium hydroxide to pH 4.54 ± 0.05, from 1.8 to 2.2 wt% benzyl alcohol and water for injections - balance.

EFFECT: invention provides high stability of preparation for up to 2 years at temperature higher than 15 degrees Celsius, as well as avoiding formation of suspension in injection solution.

4 cl, 1 ex

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RU 2 589 824 C1

Authors

Kulkin Sergej Nikolaevich

Shmeleva Varvara Nikolaevna

Dates

2016-07-10Published

2014-12-26Filed