FIELD: pharmaceutics.
SUBSTANCE: invention is a topical composition in form of an aerosol powder for treatment and/or prevention of infection of skin lesions containing silver sulfadiazine and at least one silicate, characterised in that said composition contains silver sulfadiazine in an amount from 0.1 to 5 wt% relative to total weight of composition, at least one silicate in an amount of 92 to 99 wt% relative to total weight of composition, and a pharmaceutically acceptable excipient - balance, wherein pharmaceutically acceptable excipient has a particle size less than 13 mcm, and/or 90 % of particles have a size of from 5 to 10 mcm, and/or 50 % of particles are smaller than 4 mcm and wherein silicate is selected from hydrated magnesium silicate, aluminum silicate, calcium silicate or mixtures thereof.
EFFECT: invention provides intensified therapeutic effectiveness.
11 cl, 2 dwg, 2 ex
Title |
Year |
Author |
Number |
NOVEL SYNERGISTIC PHARMACEUTICAL COMPOSITION FOR TOPICAL APPLICATION |
2010 |
- Vadrevu Krishna Mokhan
- Pelluri Venkata Cherish Babu
- Sharma Khadzhes
|
RU2571506C2 |
ANTI-INFLAMMATORY AND ANTI-ALLERGIC MEDICATION AND BASED ON IT PHARMACEUTICAL COMPOSITION |
2009 |
- Demin Aleksandr Viktorovich
- Mart'Janov Vitalij Afanas'Evich
- Shuster Aleksandr Mikhajlovich
|
RU2426540C1 |
PREPARATIONS USED FOR ADMINISTRATION OF ANTI- -INFLAMMATORY AND ESPECIALLY ANTISEPTIC AGENTS AND/OR AGENT PROMOTING TO WOUND HEALING INTO LOWER RESPIRATORY WAY |
1999 |
- Flajsher Vol'Fgang
- Rajmer Karen
|
RU2212884C2 |
ELECTROGENERATING PARTICLES AND USE THEREOF |
2008 |
- Shantala Zhannett
- Lju Tszjueh-Chehn'
- Khauschajld Dzhejms I.
- Min Sin'Tjan'
- Sautkholl Majkl
- Sun' In
|
RU2471492C2 |
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PSORIASIS |
2020 |
- Krasavin Mikhail Iurevich
- Garabadzhiu Aleksandr Vasilevich
- Zhukov Aleksandr Sergeevich
- Khairutdinov Vladislav Rinatovich
|
RU2742879C1 |
USE OF PLANT EXTRACT AS ACTIVE AGENT IN PROCESSES OF REEPITHELIZATION AND CICATRIZATION OF TISSUE |
2018 |
- Alimonti, Andrea
- Dzhori, Andrea Mariya
- Montopoli, Monika
- Kadau, Dzhessika
|
RU2782198C2 |
PREPARATIONS FOR INJECTING ANTIPHLOGISTIC, ESPECIALLY, ANTISEPTIC SUBSTANCES AND/OR THOSE FAVORING WOUND HEALING INTO SUPERIOR RESPIRATORY PATHWAYS AND/OR EAR |
1999 |
- Flajsher Vol'Fgang
- Rajmer Karen
- Kramer Aksel'
|
RU2211693C2 |
COMPOSITIONS AND METHODS OF INCREASING EFFICIENCY OF LOCAL APPLICATION OF AN ALKALINE BENEFICIAL AGENT |
2015 |
- Sun, Ying
- Wu, Jeffrey M.
- Fassih, Ali
|
RU2722783C2 |
ANHYDROUS POWDER AND LIQUID PARTICLES |
2013 |
|
RU2640184C2 |
PARTICLES FOR ACTIVE INGREDIENT DELIVERY, METHOD FOR MAKING THEREOF AND BASED COMPOSITIONS |
2007 |
- Singkh Amardzhit
- Singkh Sarabdzhit
- Singkh Paramdzhit
- Dzhain Radzhesh
|
RU2413506C2 |