PARTICLES FOR ACTIVE INGREDIENT DELIVERY, METHOD FOR MAKING THEREOF AND BASED COMPOSITIONS Russian patent published in 2011 - IPC A61K9/51 A61K9/52 A61K9/14 A61K31/522 A61K31/7056 A61K31/137 A61K31/165 A61K38/18 A61K47/02 A61K47/30 A61J3/02 A61J3/00 

Abstract RU 2413506 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a composition of microparticles or nanoparticles for local delivery and delivery to a mucous surface of an active ingredient containing 0.1-99.5 wt % of an inorganic element chosen from alkaline, earth or transition metal, lanthanide or silicon dioxide, alkoxide, oxide, oxalate, ureate, nitrate or acetate, 0.01-95 wt % of a pharmaceutical or cosmetically active ingredient, and 0.001-75 wt % of a release control agent chosen from natural, synthetic or semisynthetic polymers, polysaccharides, monosaccharides, salts, fibres or peptides. Also, the invention covers methods for making said composition which involve dissolving each ingredient in a solvent, mixing the prepared solutions, adding a solution of alkaline hydroxide and producing a dry powder composition or gel colloidal solution of nanoparticles. Besides, the invention refers to a kit comprising said composition, a delivery device and an application data sheet.

EFFECT: invention provides better fixation in an effective area, effective absorption and controlled release.

34 cl, 9 tbl, 2 dwg, 6 ex

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RU 2 413 506 C2

Authors

Singkh Amardzhit

Singkh Sarabdzhit

Singkh Paramdzhit

Dzhain Radzhesh

Dates

2011-03-10Published

2007-08-10Filed