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2 599 988

(13)

(51)

IPC

C07D243/24(2006-01-01)

C07D243/28(2006-01-01)

C07C49/786(2006-01-01)

C07C233/33(2006-01-01)

(21) (22)

Application

2015138324/04, 2015-09-08

(24)

Start date

2015-09-08

(22)

Actual filing date

2015-09-08

(45)

Published

2016-10-20

(72)

Inventor

Novakov Ivan AleksandrovichPletneva Mariya YurevnaNavrotskij Maksim BorisovichKameneva Irina YurevnaBrunilina Lejla LipparitovnaBabushkin Aleksandr Sergeevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Gosudarstvennyj Tekhnicheskij Universitet"

METHOD OF PRODUCING 7-BROMO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE Russian patent published in 2016 - IPC C07D243/24 C07D243/28 C07C49/786 C07C233/33

Abstract RU 2599988 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one - active ingredient of original domestic sedative agent "Phenazepam".

EFFECT: disclosed is a novel simpler method of producing 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one by formation from N-[4-bromo-2-(2-chlorobenzoyl)phenyl]-2-chloroacetamide and subsequent cyclocondensation of 2-amino-N-[4-bromo-2-(2-chlorobenzoyl)phenyl]acetamide.

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RU 2 599 988 C1

Authors

Novakov Ivan Aleksandrovich

Pletneva Mariya Yurevna

Navrotskij Maksim Borisovich

Kameneva Irina Yurevna

Brunilina Lejla Lipparitovna

Babushkin Aleksandr Sergeevich

Dates

2016-10-20—Published

2015-09-08—Filed