FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of diazepine of the formula (I) 
where values of radicals A, R1, X, Y and R4 are given in the invention claim and to pharmaceutical composition showing antiarrythmic activity and method of treatment of patients with arrythmia. Derivatives of diazepine show antiarrythmic activity and safety. EFFECT: valuable medicinal properties, safety. 21 cl, 6 tbl, 15 dwg, 111 ex
| Title |
Year |
Author |
Number |
| 2,3-DIHYDRO-1-(2,2,2-TRIFLUOROETHYL)-2-OXO-5-PHENYL -1H- 1,4-BENZODIAZEPINES AND METHOD OF PREVENTION OR TREATMENT OR ARYTHMIA |
1995 |
- Dehvid A.Klehremon
- Najdzhel Liverton
- Garol'D Dzh.Selnik
|
RU2149161C1 |
| SUBSTITUTED HETEROCYCLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT, PHARMACEUTICAL COMPOSITION FOR BLOCKADE OF NEUROKININ-1 RECEPTORS IN MAMMALS, METHOD OF BLOCKADE OF NEUROKININ-1 RECEPTORS IN MAMMALS |
1993 |
- Konrad P.Dorn
- Dzheffri Dzh.Khejl
- Mal'Kol'M Mehkkoss
- Sander Dzh.Millz
- Tamara Lehdduvakhetti
- Shrenik K.Shakh
|
RU2140914C1 |
| SPIROPIPERIDINES, METHODS OF THEIR SYNTHESIS (VARIANTS) |
1993 |
- Meng-Khsin Chen
- Dehvid B. R. Dzhonston
- Rehvi P. Nargund
- Artur A. Patchett
- Dzhehjms R. Tata
- Likhu Jang
|
RU2168512C2 |
| METHOD OF PREPARING 7,7-DIOXIDE 5,6-DIHYDRO (S) -4- (ALKILAMINO)-(S)-6- ALKYL-4H- THIENO (2,3-b) THIOPYRAN - 2-SULFONAMIDE AND 7,7-DIOXIDE 5,6-DIHYDRO(S)-4- (ACYLAMIDO)-(S)-6-ALKYL-4H-THIENO (2,3-b)THIOPYRAN |
1994 |
- Pol Sokhar
- Dehvid Dzh.Matr
- Tomas Dzh.Blehklok
|
RU2114851C1 |
| SUBSTITUTED MORPHOLINES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF COUNTERACTION TO SUBSTANCE P OR INHIBITION OF NEUROKININ-1 RECEPTORS |
1995 |
- Konrad P. Dorn
- Dzheffri Dzh. Khejl
- Mal'Kol'M Makkoss
- Sander G. Mills
|
RU2170233C2 |
| METHOD OF TREATMENT OF PATIENTS WITH PROSTATE BENIGNITY HYPERPLASIA, PHARMACEUTICAL PREPARATION CONTAINING INHIBITOR OF 5-ALPHA-REDUCTASE |
1992 |
- Glenn Dzh.Gomlej
- Ehlizabet Stoner
|
RU2125879C1 |
| INHIBITORS OF HIV-PROTEASE |
1994 |
- Dzhoel R.Khaff
- Dzhozef P.Vakka
- Brjus D.Dorsi
|
RU2137768C1 |
| DERIVATIVES OF PIPERAZINYLPENTAMIDE AND PHARMACEUTICAL COMPOSITION FOR INHIBITION OF HIV-PROTEASE ACTIVITY |
1992 |
- Dzhozef P.Vakka
- Brjus D.Dorsi
- Dzhejms P.Guar
- Katrin M.Khollovej
- Rehndell V.Khangejt
|
RU2131416C1 |
| METHOD FOR PRODUCTION OF TYROSINE DERIVATIVES |
1993 |
- Dzhon I.L.Chang
- Dehvid L.Kh'Judzhes
- Dehlian Zao
|
RU2113432C1 |
| DERIVATIVES OF BENZODIAZEPINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1993 |
- Khehmish Rajder
- Grehm Sempl
- Dehvid Alan Kendrik
- Majkl Zhelke
- Masato Satokh
- Mitsuaki Okhta
- Kejdzi Mijata
- Akito Nisida
|
RU2139282C1 |
