FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions concerns solid compositions containing agonist GLP-1 and salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid, where the amount of said salt is at least 0.6 or at least 0.8 mmol, and said GLP-1 agonist represents semaglutide, as well as use in medicine for treating type II diabetes or obesity.
EFFECT: group of inventions provides improved action and bioavailability.
28 cl, 1 ex, 10 tbl
Title | Year | Author | Number |
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|
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SOLID COMPOSITIONS CONTAINING GLP-1 AGONIST AND N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID SALT | 2019 |
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ORAL DOSING OF GLUCAGON-LIKE PEPTIDE-1 COMPOUNDS | 2014 |
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SOLID COMPOSITIONS FOR ORAL ADMINISTRATION | 2018 |
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DOUBLE-ACYLATED GLP-1 DERIVATIVES | 2010 |
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DIPEPTIDE, CONTAINING NONPROTEINOGENIC AMINO ACID | 2012 |
|
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NOVEL GLUCAGON ANALOGUES | 2012 |
|
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DOUBLE ACYLATED GLP-1 DERIVATIVES | 2012 |
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STABLE PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-ANTAGONISTS FOR MEDICAL USE | 2014 |
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Authors
Dates
2016-10-20—Published
2011-12-16—Filed