FIELD: pharmacology.
SUBSTANCE: invention relates to a dipeptide containing a nonproteinogenic amino acid of formula 1 , and a method of obtaining of the target polypeptide or protein, including one or more nonproteinogenic amino acids, where the specified dipeptide of formula 1 is used.
EFFECT: dipeptide has a high stability, is easy to handle and its use in the peptide chemistry is easier compared to a conventional stepped peptide synthesis in the solid phase by reducing the number of stages of chemical modification, such as protection removal and activation stages.
19 cl, 1 tbl, 4 ex
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Authors
Dates
2018-02-02—Published
2012-12-20—Filed