FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to clinical immunology, allergology and pulmonology, and can be used for enhancing the activity of nonspecific protection factors in patients with chronic obstructive pulmonary disease (COPD). For this purpose patients with COPD in a state out of aggravation of the disease are once vaccinated against pneumococcal infection with preparation "Prevenar-13".
EFFECT: method enables enhancing the activity of nonspecific protection factors due to increased phagocytic index of neutrophils, monocytes, indicator of activity of spontaneous NBT test of neutrophils, indicator of activity of induced NBT test of neutrophils, as well as increasing percentage of NBT-positive leukocytes in the spontaneous test at its safety and availability.
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