DRUG PREPARATION BASED ON INDOLE-3-CARBINOL WITH INCREASED EPIGENETIC ACTIVITY Russian patent published in 2016 - IPC A61K31/404 A61K47/12 A61K47/26 A61K47/36 A61K47/38 A61K9/56 A61P5/00 A61P15/00 A61P43/00 

Abstract RU 2601893 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry and can be used for production of medicinal agents, required in therapy of diseases of the reproductive system (pathology of mammary glands, uterus, endometrium). Therapeutic agent possessing epigenetic activity contains indole-3-carbinol and excipients: lactose, microcrystalline cellulose, modified corn starch, magnesium stearate or calcium stearate, enclosed in a capsule, which are made from hydroxypropyl methylcellulose, in the following quantity in one capsule, g: indole-3-carbinol 0.10-0.20; lactose 0.10-0.15; corn starch modified 0.05-0.15; microcrystalline cellulose 0.5-0.15; magnesium stearate or calcium stearate 0.001-0.004.

EFFECT: invention allows to increase efficiency of release of indole-3-carbinol of dosage form and its conversion into diindolylmethane, which implements its diindolylmethane activity.

1 cl, 3 dwg, 4 ex

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RU 2 601 893 C1

Authors

Kiselev Vsevolod Ivanovich

Dates

2016-11-10Published

2015-11-30Filed