FIELD: pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical industry and represents pharmaceutical preparation in form of solution for intravenous and intramuscular administration, containing drotaverine hydrochloride, sodium disulphite, buffer agent and solvent. According to invention, preparation as buffer agent contains ammonium acetate and 30 % aqueous solution of acetic acid, and solvent is 95 % ethanol and water for injections highly purified in following proportions: drotaverine hydrochloride (in terms of anhydrous substance) - 18-22 mg, sodium disulphite - 0.9-1.1 mg, ethanol 95 % (in terms of anhydrous) - 0 59.4-72.6 mg, ammonium acetate - 0.66-1.0 mg, 30 % aqueous solution of acetic acid - 0.54-1.0 mg, water for injections - up to 1.0 ml, pH - 4.0-5.5, as well as method of producing of preparation.
EFFECT: invention provides high stability of preparation and maintaining pH in process of storage.
3 cl, 4 ex
