METHOD OF INCREASING IMMUNOBIOLOGICAL REACTIVITY AND REPRODUCTIVE FUNCTION IN HEIFERS DURING ONSET OF PHYSIOLOGICAL AGEING Russian patent published in 2017 - IPC A61K36/00 A61K36/185 A61K36/28 A61K33/38 A61P37/02 A61P37/04 

FIELD: veterinary science.

SUBSTANCE: invention relates to veterinary science and aims at preventing immunodeficiency increasing immunobiological reactivity and reproductive function in heifers during onset of physiological maturity. Proposed method comprises using immunostimulating preparation in form of mixture of water-alcohol infusion of purple echinacea herb and inula rootstock prepared on basis of 70 % vol. of ethanol in ratio 1:5 and diluted to 30 vol% of distilled water, and water solution of silver, dissolved in boiled water. Preparation is given to animal orally once a day 20–30 minutes before feeding. During onset of physiological maturity in 15–16-month age tincture is allowed for 20–30 days, in a dose of 0.10–0.12 ml per 1 kg of body weight, diluted with 130–150 ml of boiled water at 180–220 kg of body weight. Water-alcohol infusion is prepared as follows: 2 parts of purple echinacea, 1 part inula rootstock and 1 part calendula flowers are mixed with 70 % vol. of ethanol, maintained during 14–15 days at temperature 36–37 °C, and water solution of silver is introduced in an aqueous-alcoholic tincture in dose of no more than 200 ml, that is no more than 8 mg of silver ions, with 100–120 ml of boiled water at 30–40 kg of body weight.

EFFECT: preparation increases reproductive function of animals.

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