METHOD FOR PREPARATION OF DRUG WITH AMBER ACID AND CETYLPYRIDINIUM CHLORIDE WITH LOCAL ACTION Russian patent published in 2017 - IPC A61K31/4164 A61K31/194 A61K33/10 A61K31/45 A61K9/40 A61P1/02 

Abstract RU 2617238 C1

FIELD: pharmacology.

SUBSTANCE: invention is a method for topical drug production for periodontal diseases treatment, comprising amber acid, cetyl pyridinium chloride, gelatin, glycerol, 1% solution of NaHCO3 and water, wherein the components are in a certain ratio per one film, in grams, including gelatin soaking in water, which is allowed to stand for 3 hours for swelling, and then heated in a water bath at 60°C until complete dissolution, at that, amber acid is dissolved in 1% solution of NaHCO3 and heated slightly to remove any air bubbles, then cetylpyridinium chloride and glycerol are added gradually to the resulting weight with stirring, and then the resulting solution is added to the cooled gelatin solution at continuous stirring, the mass stirred and left for 1 hour at room temperature to remove air, then a mould treated with 96% ethanol is filled with the resulting mass, which is spread evenly and allowed to stand for 72 hours at room temperature to dry and provide an elastic film.

EFFECT: expansion of the arsenal of drugs with prolonged action.

1 dwg, 1 tbl, 7 ex

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RU 2 617 238 C1

Authors

Nozhkina Nataliya Nikolaevna

Simonyan Elena Vladimirovna

Sinitskij Anton Ivanovich

Filimonova Olga Ivanovna

Shishkova Yuliya Sergeevna

Belousova Evgeniya Olegovna

Dates

2017-04-24Published

2016-03-30Filed