5-BROMONICOTINIC ACID DERIVATIVES WITH ANTI-ARRHYTHMIC ACTIVITY Russian patent published in 2017 - IPC C07D213/79 A61K31/455 A61P9/06 

Abstract RU 2617428 C2

FIELD: pharmacy.

SUBSTANCE: invention relates to 5-bromonicotinic acid derivatives: , where R1 is hydrogen; R2 is 4-methoxy-6-methyl-1,3,5-triazile-2, or a hydrogen proton or a 2-methyl-1,2,4-triazolyl-1. The compounds can be used in clinical practice for cardiac rhythm correction.

EFFECT: creation of a new compound with anti-arrhythmic activity.

2 tbl

Similar patents RU2617428C2

Title Year Author Number
AGENT ELICITING ANTI-ISCHEMIC, HYPOTENSIVE, ANTI- -ARRHYTHMIC AND NOOTROPIC ACTIVITY 2002
  • Berestovitskaja V.M.
  • Vasil'Eva O.S.
  • Novikov B.M.
  • Usik N.V.
  • Zobacheva M.M.
  • Tjurenkov I.N.
  • Perfilova V.N.
  • Borodkina L.E.
RU2216322C1
ANTI-ARRHYTHMIC PREPARATION 2002
  • Kutnjak Viktor Pavlovich
  • Lipnitskij Taras Nikolaevich
  • Kozlovskij Vadim Alekseevich
RU2223759C1
ANTIARRHYTHMIC PREPARATION 1999
  • Sapronov N.S.
  • Gavrovskaja L.K.
  • Eliseev V.V.
  • Krylova I.B.
  • Evdokimova N.R.
  • Kudrjashova N.I.
RU2185159C2
AGENT EXHIBITING ANTIARRHYTHMIC ACTIVITY 2014
  • Goncharova Anna Yakovlevna
  • Erimbetov Kenes Tagaevich
  • Klejmenov Aleksej Viktorovich
  • Podgorodnichenko Vladimir Konstantinovich
  • Roziev Rakhimdzhan Akhmetdzhanovich
  • Khomichenok Viktor Vladimirovich
RU2565404C1
ANTIARRHYTHMIC AGENT 1984
  • Pernikis Ruta Jakovlevna
  • Lejmane Ieva Petrovna
  • Chakste Zajga Viktorovna
  • Skorobogatov V.I.
  • Vinogradov V.M.
  • Karklin' Roman Janovich
RU2028144C1
DERIVATIVE OF 4-HYDROXYBUTYRIC ACID BENZYLAMIDE SHOWING LOCAL ANESTHETIC, ANTIARRHYTHMIC, ANTIANGIAL AND ANTINECROTIC ACTIVITY 1988
  • Tjukhteneva Z.I.
  • Badovskaja L.A.
  • Tlekhusezh M.A.
  • Linchenko S.N.
  • Bartashevich V.V.
  • Mingalev A.N.
  • Khan V.V.
  • Uvarov A.V.
  • Vas'Kov K.S.
  • Medvedev O.S.
  • Stoljarchuk A.A.
  • Galenko-Jaroshevskij A.P.
  • Ehgik'Jan A.L.
  • Timoshenko Ja.G.
  • Kubantsev A.V.
  • Shejkh-Zade Ju.R.
  • Budarin L.I.
  • Kriss E.E.
  • Arshinnikova L.L.
  • Frantsuzova S.B.
  • Tikhonova N.A.
  • Galenko-Jaroshevskij P.A.
  • Ljufi A.Ja.
  • Onopriev V.V.
  • Porotikov V.I.
  • Bukej T.I.
SU1601984A1
PHARMACEUTICAL COMBINATION FOR PREVENTION AND TREATMENT OF CHRONIC DISORDERS OF VEGETATIVE REGULATION OF HEART RHYTHM AND METHOD OF PREVENTION AND TREATMENT BY MEANS OF PHARMACEUTICAL COMBINATION 2012
  • Shkol'Nikova Marija Aleksandrovna
  • Kruglyj Boris Igorevich
  • Bereznitskaja Vera Vasil'Evna
RU2493836C1
USE OF 2-METHYLENE-1,3-DINITROXYPROPANE AS ANTI-ISCHEMIC AGENT 2015
  • Korepin Anatolij Georgievich
  • Glushakova Natalja Mikhajlovna
  • Mitrokhin Nikolaj Mikhajlovich
  • Veselov Sergej Vladimirovich
RU2580929C1
ANTIARRHYTHMIC DRUG 2017
  • Yunusov Marat Sabirovich
  • Murinov Yurij Ilich
  • Tsyrlina Elena Markovna
  • Yunusova Svetlana Grigorevna
  • Zarudij Feliks Srulevich
  • Kryzhanovskij Sergej Aleksandrovich
  • Tsorin Iosif Borisovich
RU2664668C1
APPLICATION OF GLUTARIC ACID DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AS ANTIARRHYTHMIC DRUG 2008
  • Nebol'Sin Vladimir Evgen'Evich
  • Blinov Dmitrij Sergeevich
  • Balashov Vladimir Pavlovich
  • Kromova Tat'Jana Aleksandrovna
  • Zheltukhina Galina Aleksandrovna
RU2373934C1

RU 2 617 428 C2

Authors

Karimova Rufiya Gabdelkhaevna

Garipov Talgat Valirakhmanovich

Grigoreva Svetlana Aleksandrovna

Gilmanov Ruslan Zamilevich

Petrov Evgenij Sergeevich

Petrova Svetlana Sergeevna

Khajrutdinov Farid Garafutdinovich

Sobachkina Tamara Nikolaevna

Dates

2017-04-25Published

2015-09-09Filed