NEW DERIVATIVE OF 3-(4-(BENZYLOXY)PHENYL)HEX-4-INE ACID, METHOD FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION FOR METABOLIC DISEASE PREVENTION AND TREATMENT INCLUDING IT AS EFFECTIVE INGREDIENT Russian patent published in 2017 - IPC C07D317/72 C07D213/55 C07D221/04 C07D241/04 C07D217/04 C07D209/44 A61K31/435 A61K31/357 A61K31/4035 A61K31/47 A61K31/496 A61P3/10 

Abstract RU 2628077 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to a compound represented by formula 1, its optical isomer or a pharmaceutically acceptable salt thereof: [Formula 1] , as well as to methods for its preparation and a pharmaceutical composition based on it.

EFFECT: new connections are obtained, with the ability to activate the GPR40 enzyme, suitable for use for metabolic disease prevention or treatment.

10 cl, 7 tbl, 77 ex, 2 dwg

Similar patents RU2628077C2

Title Year Author Number
COMBINATION CONTAINING NEW DERIVATIVE 3-(4-(BENZYLOXY)PHENYL)HEX-4-IN-ACID AND OTHER ACTIVE INGREDIENT TO ACTIVATE G-PROTEIN 40 OF THE RECEPTOR ENZYME 2015
  • Yan Dzhin
  • Kim Dzhin Voon
  • Li Khan Kyu
  • Kim Dzhe Khyun
  • Son Chan Mo
  • Li Kyu Khvan
  • Choj Khyun-Kho
  • Kim Dekhoon
  • Kha Te-Eun
  • Rkhee Dzhekol
RU2680248C1
NOVEL COMPOUNDS, ISOMERS THEREOF OR PHARMACUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONISTS AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUNDS 2007
  • Kim Sun-Jang
  • Kim Dzin Kvan
  • Li Ki-Vkha
  • Voo Bioung Jang
  • Shin Song Seog
  • Mokh Dzoo-Khiun
  • Kim Sung-Il
  • Dzeong Jeon Su
  • Lim Kiung Min
  • Choi Dzin Kiu
  • Kha Dzun Jong
  • Kokh Khiun-Dzu
  • Park Jang-Kho
  • Sukh Jang-Ger
  • Kim Khee-Doo
  • Park Khieung-Geun
  • Okh Ukh Taek
RU2448108C2
METHOD OF ASSESSING THE QUALITY OF (3S)-3-(4-(3-(1,4-DIOXASPIRO[4,5]DEC-7-EN-8-YL)BENZYLOXY)PHENYL)HEX-4-YNOIC ACID 2021
  • Hwang, Jeong Un
  • Lee, Kyu Hwan
  • Kim, Eun Young
  • Choi, Su Kyoung
RU2804883C1
QUINAZOLINE DERIVATIVES FOR SLOWING DOWN GROWTH OF CANCER CELLS AND METHOD OF OBTAINING THEM 2005
  • Kham Jang Dzin
  • Gong Dzi Khieon
  • Cha Mi Jang
  • Kim Dzong Voo
  • Kim Maeng Sup
  • Kim Eun Jang
  • Song Dzi Jeon
  • Kim Chang In
  • Kim Se Jang
  • Li Gvan Sun
RU2362773C2
NOVEL FUSED PYRIMIDINE DERIVATIVES FOR INHIBITION OF TYROSINE KINASE ACTIVITY 2011
  • Cha Mi Yang
  • Kang Seok Dzong
  • Kim Mi Ra
  • Li Dzu Jeon
  • Dzeon Dzi Yang
  • Dzo Mioung Gi
  • Kvak Eun Dzoo
  • Li Kvang Ok
  • Kha Tae Khee
  • Sukh Kvee Khiun
  • Kim Maeng Sup
RU2585177C2
GPR40 RECEPTOR AGONIST, METHODS OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT 2013
  • Li Sung Bae
  • Paek Seung Jup
  • Joon Sook Kiung
  • Joon Seung Khiun
  • Choj Dzeung Soon
RU2650506C2
INDOLE AND INDAZOLE DERIVATIVES SHOWING PRESERVING ACTION ON CELLS, TISSUES AND ORGANS 2009
  • Kim Soon Kha
  • Kim Khioung Dzin
  • Chung Chul Voong
  • Park Kheui Sul
  • Kvak Khio Shin
  • Kim Sung Kho
  • Park Dzin Gu
RU2460525C2
NEW PYRIDINE DERIVATIVES, METHOD FOR MAKING THEREOF AND RELATED PHARMACEUTICAL COMPOSITION 2004
  • Kim Khiung-Ook
  • Li Nam Kiu
  • Kim Dzoo Khion
  • Rkhee Khae In
  • Cho Jong-Baik
  • Riu Dze Kho
  • Kim Nam Kho
  • Riu Keun Kho
  • Ji Dzung Bum
  • Dzung Dzae Joon
RU2366659C2
INDOLE AND INDAZOLE COMPOUNDS AS CELLULAR NECROSIS INHIBITORS 2008
  • Kim Soon Kha
  • Kim Khioung Dzin
  • Koo Sun Joung
  • Chung Chul Voong
  • Li Sung Bae
  • Park Kheui Sul
  • Joon Seung Khiun
  • Kvak Khio Shin
  • Seo Dong Ook
  • Park Eok
RU2437883C1
NEW CYCLOPENTA[B]FLUORENYL COOMPOUND OF TRANSITION METAL, CATALYTIC COMPOSITION CONTAINING IT, AND METHOD FOR PRODUCTION ETHYLENE HOMOPOLYMER OR ETHYLENE AND ALPHA-OLEFIN COPOLYMER AT ITS USE 2012
  • Shin Dong Cheol
  • Li Kho Seong
  • Kim Seong Kiung
  • Li Sang Ik
  • Kim Sun Yang
  • Khakhn Dzong Sok
  • Dzeon Chan Voong
  • Kim Dzeong Khvan
RU2632895C2

RU 2 628 077 C2

Authors

Yang Dzin

Kim Dzin Voong

Li Khan Kiu

Kim Dzae Khiun

Son Chang Mo

Li Kiu Khvan

Choi Khiung-Kho

Kim Daekhoon

Kha Tae-Yang

Rkhee Dzaekeol

Dates

2017-08-14Published

2014-04-17Filed