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2 632 005

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(51)

IPC

C07D231/12(2006-01-01)

A61K31/415(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2016139886, 2016-10-10

(24)

Start date

2016-10-10

(22)

Actual filing date

2016-10-10

(45)

Published

2017-10-02

(72)

Inventor

Brel Anatolij KuzmichTyurenkov Ivan NikolaevichLisina Svetlana ViktorovnaVolotova Elena VladimirovnaPopov Sergej SergeevichVerkholyak Dmitrij Viktorovich

(73)

Holder

Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Gbou Vpo Volggmu Mz Rf

N-(ACETYLSALICYLOYL)PYRAZOL WITH CEREBROPROTECTOR ACTION IN CASE OF CEREBRAL CIRCULATION INSUFFICIENCY Russian patent published in 2017 - IPC C07D231/12 A61K31/415 A61P9/10

Abstract RU 2632005 C1

FIELD: pharmacology.

SUBSTANCE: invention can be used to obtain effective cerebroprotective agents based on pyrazole and 2-acetoxybenzoic acid (acetylsalicylic acid, aspirin). A pyrazole derivative with the formula given below is proposed. .

EFFECT: derivative has a cerebroprotective effect, effectively and in small doses improves cerebral circulation in the model of one-stage irreversible bilateral occlusion of common carotid arteries, surpasses the action of pyracetam.

3 tbl, 2 ex

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RU 2 632 005 C1

Authors

Brel Anatolij Kuzmich

Tyurenkov Ivan Nikolaevich

Lisina Svetlana Viktorovna

Volotova Elena Vladimirovna

Popov Sergej Sergeevich

Verkholyak Dmitrij Viktorovich

Dates

2017-10-02—Published

2016-10-10—Filed