OPHTHALMIC COMPOSITION FOR TREATMENT OF CONJUNCTIVITES, BLEPARITIS AND MARGINAL CORNEAL ULCERS IN TOPICAL APPLICATION Russian patent published in 2017 - IPC A61K9/10 A61K31/57 A61K33/22 A61K31/728 A61P27/02 

FIELD: pharmacology.

SUBSTANCE: invention is an ophthalmic composition containing an active substance, excipients and a consistent-forming base, characterised by containing (11beta,16alpha)-16,17-(butylidenbis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione(budesonide) and hyaluronic acid or sodium hyaluronate as an active substance, and boric acid as an auxiliary substance, the components in the composition being in a certain ratio %.

EFFECT: increased therapeutic effectiveness of the claimed composition due to the combined action of budesonide and a hyaluronic acid source with prolonged drugs action and increased contact time of the composition with the eye cornea, reduced therapy course, excluded relapses of diseases and complications, and also a low degree of absorption with more pronounced action, simplicity in performance and good tolerability of patients suffering from eye inflammatory diseases of non-infectious etiology and allergic lesions of the ocular surface.

2 cl, 4 ex