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2 634 248

(13)

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IPC

A61K36/27(2006-01-01)

A61K36/484(2006-01-01)

A61K9/02(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2016109544, 2016-03-16

(24)

Start date

2016-03-16

(22)

Actual filing date

2016-03-16

(45)

Published

2017-10-24

(72)

Inventor

Shevchenko Aleksandr MikhajlovichStarokozhko Leonid EvgenevichShchetinin Evgenij VyacheslavovichKalbazova Ekaterina VasilevnaA. Ameer DzhakhanA. Nadzheerul AmeenA. Anand KumarAshutkhosh Kumar Sing

(73)

Holder

Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Vpo Stgmu Minzdrava Rossii)Shevchenko Aleksandr MikhajlovichStarokozhko Leonid Evgenevich

RECTAL SUPPOSITORIES OF ANTIDIABETIC ACTION Russian patent published in 2017 - IPC A61K36/27 A61K36/484 A61K9/02 A61P3/10

Abstract RU 2634248 C2

FIELD: pharmacology.

SUBSTANCE: one suppository contains, g: a dense extract of forest gymnema leaves - 0.45; thick licorice root extract - 0.25; polyethylene glycol 6000 - 2.0; cremophor RH-40 - 0.30; methylparaben - 0.003; propyl paraben - 0.0005.

EFFECT: invention provides high bioavailability of the pharmacoactive components of dense extracts of forest gymnema leaves and licorice root, using the PEG-6000 hydrophilic base and solubilizing properties of cremophor RH-40, and the introduction of small amounts of parabens provides a stable dispersed system and microbial purity of preparation during storage.

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RU 2 634 248 C2

Authors

Shevchenko Aleksandr Mikhajlovich

Starokozhko Leonid Evgenevich

Shchetinin Evgenij Vyacheslavovich

Kalbazova Ekaterina Vasilevna

A. Ameer Dzhakhan

A. Nadzheerul Ameen

A. Anand Kumar

Ashutkhosh Kumar Sing

Dates

2017-10-24—Published

2016-03-16—Filed