EFFERVESCENT PHYTOMINERAL COMPLEX WITH ANTIDIABETIC ACTION Russian patent published in 2017 - IPC A61K36/28 A61K47/02 A61P3/10 

FIELD: pharmacology.

SUBSTANCE: effervescent phytomineral complex with antidiabetic action, containing an extract of forest dry gurmar, calcium carbonate, sodium chloride, potassium iodide, potassium bromide, anhydrous sodium sulfate, anhydrous magnesium sulfate, anhydrous citric acid, sodium hydrogen carbonate, trilon-B, medium molecular polyvinylpyrrolidone, polyethylene glycol with a molar mass of 6000, MAE 100P kolliecoat. The complex contains acidic and carbonate fractions obtained by separate granulation, where the acid fraction includes an extract of forest dry gurmar, citric acid, sodium chloride, potassium chloride, anhydrous sodium sulfate, anhydrous magnesium sulfate, and the carbonate fraction includes sodium bicarbonate, calcium carbonate, potassium iodide and potassium bromide. At the stage of carbonate fraction formation, prior to granulation, trilon-B, medium molecular polyvinylpyrrolidone are added to the carbonate fraction, after carbonate fraction granulation, polyethylene glycol 6000 is added to it, and MAE 100P kolliecoat is added to the composition of the acid fraction for granulation. The complex contains components at a certain ratio.

EFFECT: complex has improved adsorption, has a predictable and stable pharmacokinetic profile, transport time in the small intestine is reduced to 20 minutes.

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