METHOD FOR TREATMENT OF VASCULARIZED CORNEAL LEUKOMA RESULTING FROM EYE BURN INJURY Russian patent published in 2017 - IPC A61K38/02 A61P27/02 

FIELD: medicine.

SUBSTANCE: for method implementation, a peptide preparation is placed in the conjunctival cavity: from the first to the 14th day - six times within an hour with a 10 minute interval between instillations, then from the 14th to the 30th day - four times within an hour with an interval of 20 minutes. To produce a peptide solution, a mononuclear fraction of bone marrow cells is isolated. The mononuclear cell suspension is then plated on petri dishes and cultured in DMEM medium supplemented with 10% fetal bovine serum. After obtaining of a cellular monolayer, the culture medium is completely changed and after 3 days the conditioned culture medium is combined with the lysate of mesenchymal stem cells (MSC). The cell culture is destroyed using physical and chemical methods.

EFFECT: restoration of the cornea transparency, achievement of complete and persistent regression of corneal neovascularization, non-invasive treatment.

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