FIELD: medicine.
SUBSTANCE: invention can be used in an experiment on animals with transplanted tumours to achieve a pronounced antitumour effect. The method includes the combined effect of magnetite nanoparticles (MN) and a low-intensity infra-low-frequency electromagnetic field. During the course of treatment, animals with tumours are administered with MN in the form of a magnetic fluid diluted with physiological saline to the MN concentration equal to 6.2 mg/ml and in a dose of 17.7 mg/kg, based on the weight of MN, subcutaneously to the zone spaced 1.5 cm from the tumour boundaries for 3 weeks, once every 3 days. In addition, a daily exposure to the animal's head is carried out for 4 weeks with infra-low frequency electromagnetic radiation in a repeated five-day cyclic regime. Every day, signals of three different frequencies are used - 0.03, 0.3 and 9 Hz, so that the exposure of the signals with a frequency 0.3 and 9 Hz is 1 minute, and the exposure of the signal with a frequency of 0.03 Hz during the cycle is 3, 4, 5, 3 and 4 minutes successively, with magnetic induction during a cycle varying from 3.2 to 0.7 mT.
EFFECT: allows to achieve a pronounced antitumour and antistress effect.
2 tbl
Title | Year | Author | Number |
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METHOD OF TREATING MALIGNANT NEW GROWTHS IN EXPERIMENT | 2010 |
|
RU2474884C2 |
METHOD OF EXPERIMENTAL TREATMENT OF MALIGNANT NEOPLASMS | 2004 |
|
RU2286811C2 |
METHOD FOR TREATING MALIGNANT NEOPLASMS UNDER EXPERIMENTAL CONDITIONS | 2003 |
|
RU2261733C2 |
METHOD OF TREATING MALIGNANT NEOPLASMS IN EXPERIMENT | 2010 |
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RU2475865C2 |
METHOD OF TREATING LUNG CANCER IN EXPERIMENT | 2009 |
|
RU2405595C2 |
METHOD FOR TREATMENT OF MALIGNANT NEOPLASMS USING ELECTROMAGNETIC INFLUENCES IN EXPERIMENT | 2004 |
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RU2289446C2 |
METHOD OF PREDICTING TUMOR GROWTH IN AN EXPERIMENT | 2017 |
|
RU2670656C9 |
TREATMENT METHOD OF PATIENTS WITH BREAST CANCER | 2008 |
|
RU2368407C1 |
METHOD FOR TREATING CANCER PATIENTS | 1996 |
|
RU2155616C2 |
COMBINED METHOD FOR TREATING MALIGNANT TUMORS | 1999 |
|
RU2175564C2 |
Authors
Dates
2017-12-13—Published
2016-07-20—Filed