METHOD FOR TREATING MALIGNANT NEW GROWTHS IN EXPERIMENT Russian patent published in 2017 - IPC A61N2/04 A61K33/26 A61P35/00 B82B1/00 G09B23/28 

Abstract RU 2638448 C1

FIELD: medicine.

SUBSTANCE: invention can be used in an experiment on animals with transplanted tumours to achieve a pronounced antitumour effect. The method includes the combined effect of magnetite nanoparticles (MN) and a low-intensity infra-low-frequency electromagnetic field. During the course of treatment, animals with tumours are administered with MN in the form of a magnetic fluid diluted with physiological saline to the MN concentration equal to 6.2 mg/ml and in a dose of 17.7 mg/kg, based on the weight of MN, subcutaneously to the zone spaced 1.5 cm from the tumour boundaries for 3 weeks, once every 3 days. In addition, a daily exposure to the animal's head is carried out for 4 weeks with infra-low frequency electromagnetic radiation in a repeated five-day cyclic regime. Every day, signals of three different frequencies are used - 0.03, 0.3 and 9 Hz, so that the exposure of the signals with a frequency 0.3 and 9 Hz is 1 minute, and the exposure of the signal with a frequency of 0.03 Hz during the cycle is 3, 4, 5, 3 and 4 minutes successively, with magnetic induction during a cycle varying from 3.2 to 0.7 mT.

EFFECT: allows to achieve a pronounced antitumour and antistress effect.

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RU 2 638 448 C1

Authors

Kit Oleg Ivanovich

Shikhlyarova Alla Ivanovna

Zhukova Galina Vitalevna

Barteneva Tatyana Albertovna

Bragina Marina Igorevna

Shirnina Elena Alekseevna

Kurkina Tatyana Anatolevna

Dates

2017-12-13Published

2016-07-20Filed