TREATMENT USING ESLICARBAZEPINE ACETATE OR ESLICARBAZEPINE Russian patent published in 2017 - IPC A61K31/55 A61P25/08 A61K45/00 

FIELD: pharmacology.

SUBSTANCE: method of partial-onset seizure treatment is offered. It is for the patient, which suffers from the absence seizures or is vulnerable to absence seizures. The method comprises the intake of the harmless and effective quantity of the eslicarbazepine acetate (or the intake of the containing it pharmaceutical composition - version), where the partial-onset seizures are accompanied by or go without the secondary generalization, where the vulnerable to absence seizures patient is a child or a teenager (versions).

EFFECT: decrease of the critical calcium current on the cells HEK-293, spontaneous absence seizures reduction and absence of GABA current amplification in contrast with the carbamazepine, which increases the absence seizures and causes the worsening of the absence seizures in rats.

18 cl, 4 tbl, 3 dwg, 4 ex