FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to the bifunctional peptide capable of activating collagen synthesis and inhibiting matrix metalloproteinase production, and can be used in medicine and cosmetology. Bifunctional peptide has a sequence of three peptide regions a, b, and c. The first region A is hexapeptide, repeated at least three times, capable of communicating with an elastin-binding receptor protein to stimulate collagen synthesis. The second region B is tetrapeptide capable acting as a competitive inhibitor of urokinase protease and cleaving by the said protease. The third region C is tripeptide that occupies at least one active site of matrix metalloproteinases to permit inhibition of these proteinases.
EFFECT: invention allows to effectively stimulate collagen synthesis and inhibit the production of matrix metalloproteinases for treatment of chronic cicatricial diseases, sores, or ulcers for skin tissue recovery or regeneration and for skin anti-aging.
18 cl, 7 ex, 8 dwg
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