APPLICATION OF AROMATIC AZOMETHINES WITH HIGHER ALKYL SUBSTITUENTS AS MEANS OF BACTERICIDAL AND FUNGICIDAL ACTIVITY Russian patent published in 2018 - IPC C07C251/24 A61K31/135 

FIELD: pharmacology.

SUBSTANCE: invention relates to application of aromatic azomethines (1-6) based on 4-((hexadecylimino)methyl)phenol (1), 4-bromo-2-((hexadecylimino)methyl)phenol(2), 4-((hexadecylimino)methyl)benzene-1,2-diol (3), N-(4-bromobenzylidene) hexadecane-1-amine (4), N-(4-chlorobenzylidene)hexadecane-1-amine (5) and N-(4-nitrobenzolidene)hexadecane-1-amine (6) of the general formula I

R¹=R²=R⁴=H, R³=OH (1), R¹=OH, R²=R³=H, R⁴=Br (2), R¹=R⁴=H, R²=R³=OH (3), R¹=R²=R⁴=H, R³=Br (4), R¹=R²=R⁴=H, R³=Cl (5), R¹=R²=R⁴=H, R³=NO₂ (6) as means having bactericidal and fungicidal activity. The invention can find application in veterinary medicine, medicine and agriculture.

EFFECT: aromatic azomethines are highly effective against pathogenic microflora at low concentrations.

5 dwg, 1 tbl, 7 ex