FIELD: nanotechnology; medicine.
SUBSTANCE: invention relates to nanotechnology, medicine, pharmacology and veterinary medicine and describes a method for preparing metronidazole nanocapsules in a shell of carrageenan. Method is characterized in that a metronidazole powder is added to the carrageenan suspension in petroleum ether in the presence of 0.01 g of E472c preparation as a surfactant, then 10 ml of chloroform are added, the resulting nanocapsule suspension is filtered off and dried, herewith the mass ratio of the core to the shell in terms of dry substance is 1:1, 1:3, 5:1 or 1:5.
EFFECT: method provides simplifying and accelerating the process of nanoencapsulation, while reducing accompanying loss.
1 cl, 1 dwg, 4 ex
Authors
Dates
2018-03-05—Published
2015-09-22—Filed