METHOD FOR PRODUCING NANOCAPSULES OF METRONIDAZOLE IN CARRAGEENAN Russian patent published in 2018 - IPC A61K31/4164 A61K47/36 A61K9/51 A61J3/07 B82B3/00 

Abstract RU 2646482 C2

FIELD: nanotechnology; medicine.

SUBSTANCE: invention relates to nanotechnology, medicine, pharmacology and veterinary medicine and describes a method for preparing metronidazole nanocapsules in a shell of carrageenan. Method is characterized in that a metronidazole powder is added to the carrageenan suspension in petroleum ether in the presence of 0.01 g of E472c preparation as a surfactant, then 10 ml of chloroform are added, the resulting nanocapsule suspension is filtered off and dried, herewith the mass ratio of the core to the shell in terms of dry substance is 1:1, 1:3, 5:1 or 1:5.

EFFECT: method provides simplifying and accelerating the process of nanoencapsulation, while reducing accompanying loss.

1 cl, 1 dwg, 4 ex

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RU 2 646 482 C2

Authors

Krolevets Aleksandr Aleksandrovich

Dates

2018-03-05Published

2015-09-22Filed