FIELD: chemistry.
SUBSTANCE: present invention relates to pyrazolopyridine derivatives of formula (I), wherein A is aryl selected from the group consisting of pyridyl, phenyl, pyrazinyl, pyridazinyl, pyrazole, triazole, indolyl, benzimidazolyl and isoquinolinyl; -B-C is -NR2-(C=O) or -(C=O)-NR2-, and the other symbols and radicals are as defined in the claims. Said compounds have blocking activities of voltage gated sodium channels, such as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved.
.
EFFECT: present invention also relates to a pharmaceutical composition comprising said compounds, and the use of said compounds and compositions in the prevention or treatment of diseases in which voltage gated sodium channels are involved.
15 cl, 10 tbl, 649 ex
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